Danay García
— Loca
Danny Trejo
— Antonio
Lou Diamond Phillips
— Casper
Steven Bauer
— Ronaldo
Bianca A. Santos
— Inez
Brandon Soo Hoo
— Gizmo
Emilio Rivera
— Carlos Santiago
Jessica Marie Garcia
— Peaches
Angelique Rivera
— Cammy
Stephanie Sanditz
— Nurse Gretchen
Victor Ortiz
— Manny
Mariano Mendoza
— Oso (as Mariano Mendoza)
Cuete Yeska
— Bull Dog
Jonathan LaVallee
— Detective Harris
Daniel Edward Mora
— Cuete
Karina Junker
— Dancer
Wilson Ramirez
— Jailhouse Sicario
H.C. Fletcher
— Byron Key (as Fletcher)
Erin Evans
— Ruby Sommerset
Sierra Reyes
— Angel's Girl
Cesar Garcia
— Angel