John Travolta
— Danny Zuko
Olivia Newton-John
— Sandy Olsson
Jeff Conaway
— Kenickie (archive footage)
Barry Pearl
— Doody
Michael Tucci
— Sonny
Kelly Ward
— Putzie
Stockard Channing
— Betty Rizzo
Didi Conn
— Frenchy
Jamie Donnelly
— Jan
Dinah Manoff
— Marty Maraschino
Eddie Deezen
— Eugene Felsnic
Susan Buckner
— Patty Simcox
Lorenzo Lamas
— Tom Chisum
Dennis Stewart
— Leo 'Craterface' Balmudo (archive footage)
Annette Charles
— Charlene 'Cha Cha' DiGregorio (archive footage)
Eve Arden
— Principal McGee (archive footage)
Dody Goodman
— Blanche Hodel (archive footage)
Sid Caesar
— Coach Calhoun (archive footage)
Alice Ghostley
— Mrs. Murdock (archive footage)
Darrell Zwerling
— Mr. Lynch (archive footage)
Dick Patterson
— Mr. Rudie
Fannie Flagg
— Nurse Wilkins
Ellen Travolta
— Waitress
Frankie Avalon
— Teen Angel
Edd Byrnes
— Vince Fontaine