Mary Pickford
— Mrs. Nordell - Heroine of the Movie within the Movie, 'The Wife's Desertion'
Edward LeSaint
— John Crawford - the Poor Husband
William E. Shay
— Wilbur Robinson - the Wife's New Lover
Lucille Young
— Mrs. John Crawford - the Poor Man's Wife
J. Farrell MacDonald
— Louis Nordell
Hayward Mack
— Ronald Seymour (as H.S. Mack)