Edward G. Robinson
— Nick 'Nicky' Donati
Bette Davis
— Louise 'Fluff' Phillips
Humphrey Bogart
— Turkey Morgan
Wayne Morris
— Ward 'Kid Galahad' Guisenberry
Jane Bryan
— Marie Donati
Harry Carey
— Silver Jackson
William Haade
— Chuck McGraw
Soledad Jiménez
— Mrs. Donati
Joe Cunningham
— Joe Taylor
Ben Welden
— Buzz Barett
Joseph Crehan
— Brady
Veda Ann Borg
— The Red Head
Frank Faylen
— Barney
Harland Tucker
— Gunman
Bob Evans
— Sam McGraw
Hank Hankison
— Burke
Bob Nestell
— O'Brien
Jack Kranz
— Denbaugh
George Blake
— Referee
Al Bain
— Boxer (uncredited)
Jack Adair
— Party Guest (uncredited)
William Arnold
— Reporter at Press Conference (uncredited)
Sam Bagley
— Cornerman (uncredited)
Don Barclay
— Drunk in Dressing Room (uncredited)
Curtis Benton
— Announcer (uncredited)
Phil Bloom
— Minor Role (uncredited)
Willie Bloom
— Minor Role (uncredited)
William A. Boardway
— Fight Spectator (uncredited)
Don Brodie
— Reporter in Hotel Lobby (uncredited)
Harry Burkhardt
— Reporter (uncredited)