Ruby LaRocca
— Trash (segment "Slay Ride")
George Stover
— Dr. Schoal (segment "One Foot in the Grave")
Izzie Harlow
— Slutpira
Countess Samela
— Lucia (segment "Blood Witch")
Josh Lively
— Derek (segment "Mike Wuz Here")
Kert Rats
— Juan Carlos (segment "Blood Witch")
Gram Parsons
— Juan Domingo (segment "Blood Witch")
Monica Puller
— Isabella / Blood Witch (segment "Blood Witch")
Cassandra Complex
— Juana / Carla (segment "Blood Witch")
Priscilla Lee Press-On
— Kelly
Amanda Garcia
— Mrs. Kellysworth (segment "Blood Witch")
Floyd Plimpton
— Telemarketer (segment "Blood Witch")
D.A. Meadows
— Bug Man (segment "Blood Witch")
T.J. Rogers
— Mike (segment "Blood Witch")
Zack Boyce
— Alex (segment "Blood Witch")
Chris Rhodes
— Gene (segment "Mike Wuz Here")
Heather Lucas
— Lydia (segment "Mike Wuz Here")
Ashley Goddard
— Gretchen (segment "Mike Wuz Here")
Jordan Hess
— Greg (segment "Mike Wuz Here")
Steven McElroy
— Frank (segment "Mike Wuz Here")
Ryan Stocking
— Roy (segment "Mike Wuz Here")
Amber Eakin
— Jailbait #1 (segment "Mike Wuz Here")
Tara Mayle
— Jailbait #2 (segment "Mike Wuz Here")
Sara Cole
— Katie (segment "One Foot in the Grave")
Virginia House
— Agatha (segment "One Foot in the Grave")
Dan Koenig
— Chip (segment "One Foot in the Grave")
Jimmy George
— Victim (segment "One Foot in the Grave")
Jill George
— Toes & Hoes Feet (segment "One Foot in the Grave")
Sandy Behre
— Debbie (segment "Slay Ride")
George Hrab
— Nathan (segment "Slay Ride")