Jennifer Runyon
— Melanie (segment "Epidemic")
Lynn Lowry
— Susan McKay (segment "By Proxy")
Felissa Rose
— Witch (segment "Epidemic")
Helene Udy
— Sonya Hamilton (segment "Epidemic")
Laurene Landon
— Miss Tate (segment "Radical Video")
Ari Lehman
— Edmond Blackburn (segment "Epidemic")
Jonathan Tiersten
— The Sledgehammer (segment "Radical Video")
Christopher Showerman
— The Driver (wraparound story)
Yan Birch
— Satan
Ashley Park
— Alisha Harding (segment "Radical Video")
Heath C. Heine
— Police Officer (segment "By Proxy")
Josh Outzen
— Grocery Delivery Guy (segment "By Proxy")
Hilarie Grace
— Annoyed Customer in Line 4 (segment "Radical Video")
Vivienne Bersin
— Nostalgic Video Store Customer (segment "Radical Video")
Mark Canjar
— Coroner (segment "Radical Video")
Alec Ybarra
— Soccer Kid (segment "By Proxy")
Aeon Cruz
— Nostalgic Video Store Customer (segment "Radical Video")
Josh Feldman
— Soccer Kid (segment "By Proxy")
Bekah Jung
— Geisha Girl (segment "Epidemic")
Alaina Garland
— Vickie Summers (segment "Radical Video")
Allie Escaffi
— LFGR News Reporter Vera Drake (segment "Radical Video")
Olivia Crist
— 16th Century Villager (segment "Epidemic")
Jewel Cavazos
— Samantha McKenny (segment "Radical Video")
Pam Renall
— Kristen / Annoyed Customer in Line 2
Madeleine Ours
— Possessed Fiancée (segment "Epidemic")
Karen E. Thomas
— Dr. Pamela Myers (segment "By Proxy")
Bailey Sorrel
— Maya (wraparound story)
Ella Madison
— Soccer Kid (segment "By Proxy")
Ben Hilzer
— Blaine Moore (segment "Radical Video")
Kevin Sean Ryan
— Church Show Host (segment "Epidemic")