Toby Huss
— Heckle (voice)
Bobcat Goldthwait
— Jeckle (voice)
Dee Bradley Baker
— Dinky Duck / Mighty Mouse / Sidney (voice)
Billy West
— Deputy Dawg / Stanley / Creeper (voice)
Charlie Adler
— Vincent Van Gopher (voice)
Rob Paulsen
— Muskie / Cleo (voice)
Haley Joel Osment
— Tom Terrific (voice)
Robert Taylor
— Demon (voice)