Queenpins

Kristen Bell

— Connie Janikowski

Kirby Howell-Baptiste

— JoJo

Vince Vaughn

— Simon Kilmurry

Paul Walter Hauser

— Ken

Joel McHale

— Rick

Bebe Rexha

— Tempe Tina

Dayo Okeniyi

— Earl

Nick Cassavetes

— Captain Pain

Michael Masini

— SWAT Agent Harris

Paul Rust

— Albert Anderson

Eduardo Franco

— Greg (Cashier)

Marc Evan Jackson

— Dr. Girard

Lidia Porto

— Mrs. Flores

Greta Oglesby

— Mama Josie

Jack McBrayer

— Agent Park

Annie Mumolo

— Crystal

Bill Glass

— Jail Guard Jones

Dustan Costine

— Sandman

Rooter Wareing

— Rattlesnake

Stephen Root

— Agent Flannigan

Nneoma Sampson

— Makeup Client

Tricia Fukuhara

— Cashier Nevada

Ilia Isorelýs Paulino

— Rosa

Quincy Cho

— Checkout Cashier

Rosie Garcia

— Nurse (Sperm Bank)

Ross Kimball

— SWAT Agent