Naga Chaitanya Akkineni
— Karthik
Samantha Ruth Prabhu
— Jessie Thekekuttu
Krishnudu
— Krishna
Sapan Saran
— Nandini
Sanjay Swaroop
— Raghava Rao Sivakumar
Sudheer Babu
— Jerry
Surekha Vani
— Karthik's mother
Devan
— Joseph
Lakshmi Ramakrishnan
— Teresa
Puri Jagannadh
— Self
Gautham Menon
— Self
Silambarasan
— Self
Trisha Krishnan
— Self
VTV Ganesh
— Self
Subbalakshmi
— Jessie's Grandmother