Rajinikanth
— Baba / Mahavatar Babaji
Goundamani
— Annamalai
Manisha Koirala
— Chamundeeswari
M. N. Nambiar
— Baba's Maternal Uncle
Amrish Puri
— Guruji
Vijayakumar
— Chamundeeswari's Father
Delhi Ganesh
— Perusu
Vasu Vikram
— Baba's friend
Akash
— Hussain
Karunas
— Samundi
Crane Manohar
— Kathirika
N. Viswanathan
— Baba's Father
Kitty
— Gaffar Bhai
Riyaz Khan
— Ramaswamy's Son
Bharathi Mani
— Kandhan
Ashish Vidhyarthi
— Ippo Ramaswamy
Sayaji Shinde
— Beggar / Divyananda Bharathi
Bharat Dabholkar
— CM Purushothaman
Sujatha
— Baba's Mother
Sanghavi
— Lakshmi
Seema
— Jagadeeshwari
Keiko Mayata
— Keiko
Radha Ravi
— Minister of Tourism (Special Appearance)
Ramya Krishnan
— Neelambari (Special Appearance)
Nassar
— Surya Prakash (Special Appearance)
Sarath Babu
— Father of girl saved by Baba (Special Appearance)
Deepa Venkat
— Saradha
Santhoshi
— Rajeshwari
Vaishnavi
— Bhuvaneshwari