Nur Fathiah Diaz
— Upin / Ipin (voice)
Amir Izwan
— Badrol (voice)
Kee Yong Pin
— Lim (voice)
Ida Rahayu
— Oopet / Mystic Voice (voice)
Shafiq Isa
— Uncle Muthu / Singh / Mystic Voice (voice)
Abu Shafian Abdul Hamid
— Tok Dalang (voice)
Hajah Ainon Ariff
— Opah (voice)
Rajab Abdul Rahman
— Ah Tong (voice)
Ros Hasrol Ahmad
— Salleh (voice)
Kannan Rajan
— Rajoo (voice)
Balqis Fadhullah Lee
— Sister Ros (voice)
Anas Abdul Aziz
— Sapy / Rembo / Atan / Baby Oopet / Mystic Voice (voice)
Safrizan Mohd Razali
— Zarien Farein / Mystic Voice (voice)
Tan Sheik Wei
— Lucy (voice)
Ehsan Azharuddin
— Poacher (voice)
Burhanuddin Radzi
— Bus Driver (voice)
Azfaren Aznam
— Mystic Voice (voice)