Justin Long
— Hal Nestor
Wendie Malick
— Nancy Nestor
Ed Begley Jr.
— Dr. Curly Weeks
Stephen Root
— Dwight Nestor
Danica McKellar
— Lacy Baldwin
Megan Cavanagh
— Charlene Hobbs
Mark DeCarlo
— Officer Hunter
Tippi Hedren
— Babe
Clint Howard
— Mr. Goss
Sam Huntington
— Bic
Shirley Jones
— Aunt Sis
Joel David Moore
— Rolf (as Joel Moore)
J. Bretton Truett
— Dr. Van Heisen
Travis Wester
— Rudy