Danni Smith
— Alison
Hannah Starr
— Medium Alison
Stella Rose Hoyt
— Small Alison
Rob Lindley
— Bruce Bechdel
McKinley Carter
— Helen Bechdel
Preetish Chakraborty
— John Bechdel
Leo Gonzalez
— Christian Bechdel
Danielle Davis
— Joan
Joe Lino
— Roy / Mark / Pete / Bobby Jeremy
Jeanine Tesori
— Herself
Lisa Kron
— Herself