Nathan West
— Charles Anderson
Colm Meaney
— H.L. Mencken
Brian Dennehy
— Clarence Darrow
Fred Thompson
— William Jennings Bryan
Ashley Johnson
— Rose Williams
JR Bourne
— George Rappleyea
Khori Faison
— Abigail
Thomas D. Mahard
— Judge Raulston
Geoffrey Beauchamp
— Dr. Morganthall
Jamie Kolacki
— John Scopes
Frank Zieger
— Tom Stewart
Marty Bufalini
— Mr. Lebarron
Jennifer Weil
— Mrs. Bryan
John Lepard
— Rev. Sutherland
John Sanders
— Prof. Mabon
Dan John Miller
— Mr. Shelton
Johnny Ginger
— 'Doc' Robinson
Linda Boston
— Sally
Sam Urich
— Howard
Tevis R. Marcum
— Mr. Riley
Joe Amos
— Conductor
Lauren Mae Shafer
— Trial Stenographer
Ralph Lister
— Dr. Metcalf
Gary T. Jones
— Camera Operator