Roma Downey
— Annie Sullivan
Moira Kelly
— Helen Keller
Christina Pickles
— Kate Keller
Mike Doyle
— Peter Fagan
Tom Bower
— Uncle Ed
Billy Campbell
— John Macy
Peggy Freisen
— Ida
T. Max Graham
— Dr. Charles Copeland
Jennifer Mays
— Lenore Kinney
David Rees Snell
— William Alexander
Brian Paulette
— Phillip Smith
Michael Linsley Rapport
— Editor
Glenn Q. Pierce
— Minister
Dana Vranic
— Mildred Keller
Nick Schlyer
— Warren Tyson
Dean Vivian
— Harry Weber
Bob Denison
— Dr. Flannigan
Kyla Pratt
— Young Helen