Kim Basinger
— Mother Bear (voice)
Catherine O'Hara
— Mayor Owl (voice)
Martin Short
— Justin Beaver (voice)
Jeremy Renner
— Lieutenant Timber (voice)
Mena Suvari
— Mena Vulpes (voice)
Michael J. Fox
— Michael J. Bird (voice)
Eugene Levy
— Fire Chief Ducky (voice)
Norm Macdonald
— Grandpaws (voice)
Ed Asner
— Peter Lionsbridge (voice)
Marlon Wayans
— Mr. Tortoise (voice)
Bill Burr
— Officer Quill (voice)
Tom Green
— Tom O'Malley (voice)
Harland Williams
— Reefer Harfish (voice)
Howie Mandel
— Father Bear (voice)
Tantoo Cardinal
— Mrs. Grey Horns (voice)
Sherri Shepherd
— Mrs. Tortoise (voice)
Scott Thompson
— Principal Alters (voice)
Gordon Pinsent
— Jack Rabbit (voice)
Lorne Cardinal
— Mr. Grey Horn (voice)