Roland Winters
— Charlie Chan
Keye Luke
— Lee Chan
Mantan Moreland
— Birmingham Brown
Victor Sen Yung
— Tommy Chan
Carol Forman
— Sonia Cabot
Robert Livingston
— John Stanley
Nils Asther
— Paul Evans
Beverly Jons
— Joan Farnsworth
Martín Garralaga
— Pedro Francisco Lopez
George J. Lewis
— Juan Gonzalez
Leslie Denison
— Henry Farnsworth
Erville Alderson
— Prof. Scott (uncredited)
Jay Silverheels
— Diego (uncredited)
Charles Stevens
— Manuel (uncredited)
Fred Cordova
— Filippe (uncredited)
Juan Duval
— Dr. Castalara (uncredited)
Frank Leyva
— José (uncredited)