Marguerite Clark
— Little Eva St. Clair / Topsy
Sam Hardy
— Simon Legree
Jack W. Johnston
— Haley
Florence Carpenter
— Eliza Harris
Frank Losee
— Uncle Tom
Phil Ryley
— Marks
Harry Lee
— Jeff
Walter P. Lewis
— Simon Legree
Augusta Anderson
— Mrs. St. Clair
Ruby Hoffman
— Cassy
Susanne Willis
— Aunt Chloe
Mrs. Priestly Morrison
— Ophelia
Thomas Carnahan Jr.
— George Shelby Jr.
Jere Austin
— George Harris
Henry Stanford
— Mr. St. Clair
