Buya Hamka

Vino G. Bastian

— Buya Hamka

Laudya Cynthia Bella

— Siti Raham

Donny Damara

— Haji Rasul

Desy Ratnasari

— Ummi Safiah

Marthino Lio

— Amir

Anjasmara

— Soekarno

Verdi Solaiman

— Abdul Karim/ Oei Tjeng Hien

Bima Azriel

— Rusydi (young)

Zayyan Sakha

— Zaki (young)

Mawar Eva De Jongh

— Kulsum

Mellya Baskarani

— Aminah

Yoriko Angeline

— Ola

Novita Hardini

— Fatimah

Wafda Saifan Lubis

— Rozak

Yoga Pratama

— Zaki

Roy Sungkono

— Rusydi

Ajil Ditto

— Fakhri

Alfie Alfandy

— Dadang

Donny Kesuma

— Ayah Kulsum

Ade Firman Hakim

— Karta

Ben Kasyafani

— Zainuddin Labai

Ferry Salim

— Gubernur Nakashima

Carmela van der Kruk

— Dutch Army Commander

Rasyid Albuqhory

— Rusydi Hamka

Raditya Albuqhari

— Zaki Hamka

Ivan Leonardy

— Ayah Ola

Sulistyo Kusumawati

— Ibu Ola