Sondra Locke
— Nikki Morrison
Robert Townsend
— Manny
Larry Hankin
— Robert Jewell
Sydney Lassick
— Lee 'Dial-A-Prayer'
Gerrit Graham
— Billy Morrison
Sharon Baird
— Ratboy (as S. L. Baird)
Louie Anderson
— Omer Morrison
John Witherspoon
— Heavy
Gary Riley
— Bill
Brett Halsey
— Mr. Manes
Jon Lovitz
— Party Guest
Bill Maher
— Party Guest
Karen Lorre
— Party Guest (as Karen Witter)
Kathleen Wilhoite
— Party Guest
Courtney Gains
— Kid in Car
Billie Bird
— Psychic
Lloyd Nelson
— Reporter at Dump
Lee de Broux
— Catullus Cop #2
Jeffrey Josephson
— Catullus Cop #3
Peter Looney
— Catullus Cop #4
Tiger Haynes
— Derelict Ralph
Tim Thomerson
— Alan Reynolds
Ed Williams
— Lake Reporter
Christopher Hewett
— Acting Coach
Charles Bartlett
— Catullus Cop
Gordon Anderson
— Ratboy (Voice)
Nina Blackwood
— MTV Vee-Jay
Damita Jo Freeman
— Louisa
Lisa Cloud
— Zu-Zu
Winifred Freedman
— Girlfriend