Nick Nolte
— Matt Hobbs
Whittni Wright
— Jeannie Hobbs
Albert Brooks
— Burke Adler
Julie Kavner
— Nan Mulhanney
Joely Richardson
— Cathy Breslow
Tracey Ullman
— Beth Hobbs
Jeb Brown
— Male D Person
Joely Fisher
— Female D Person
Vicki Lewis
— Millie
Anne Heche
— Claire
Ian McKellen
— John Earl McAlpine
Joel Thurm
— Martin
Angela Alvarado
— Lucy
Dominik Lukas-Espeleta
— Ricky
Justina Hardesty
— Essa
Robert Joy
— U.S. Marshal
Maria Pitillo
— Flight Attendant
Suzzanne Douglas
— Rainbow House Star
Joseph Malone
— Assistant Director
Jake Busey
— Burke's Fired Driver
Harry Shearer
— Audience Research Captain
Rosie O'Donnell
— Makeup
Ken Page
— Hair Person
Chelsea Field
— Screentest Actress
Justine Shapiro
— Studio Executive
Amy Brooks
— Shannon
Ian Deitchman
— Popcorn Pictures P.A.
Maria Kavanaugh
— Secretary on Telephone
Peter Kwong
— Popcorn Pictures Intern
Roz Baker
— Taxi Driver