Christopher Reeve
— Father John Flaherty
Geneviève Bujold
— Clara
Fernando Rey
— Cardinal Santoni
Jason Miller
— Don Vito Appolini
Adolfo Celi
— Cardinal Vinci
Leonardo Cimino
— The Pope
Tomas Milian
— Father Francisco
Robert Prosky
— Bishop Walkman
Joe Pantoliano
— Pvt. Joe Musso
Milena Vukotić
— Sister Verna
Ian Danby
— Lieutenant
Harrison Muller Jr.
— 2nd Soldier
David Mills
— Major
Joe Cortese
— Ludovico 'Lodo' Varese
Gregory Snegoff
— 1st Soldier
Joe Spinell
— Bride's Father
Pamela Prati
— 1st Roman Girl
Ritza Brown
— Maid of Honor
Loredana Grappasonni
— Bride
Ettore Mattia
— Pietro
Carolyn De Fonseca
— 1st Flaherty Secretary
Yanti Somer
— 2nd Flaherty Secretary
Mimmo Poli
— Sicilian Priest
Anny Papa
— 2nd Roman Girl
Stefania D'Amario
— 3rd Roman Girl
Elio Bonadonna
— 1st Killer
Giovanni Bonadonna
— 2nd Killer
Remo De Angelis
— 3rd Killer
Michele Messina
— 1st Sicilian Guard
Agnès Nobecourt
— 1st Postulant