Nigel Terry
— Caravaggio
Sean Bean
— Ranuccio
Garry Cooper
— Davide
Dexter Fletcher
— Young Caravaggio
Spencer Leigh
— Jerusaleme
Tilda Swinton
— Lena
Nigel Davenport
— Giustiniani
Robbie Coltrane
— Scipione Borghese
Michael Gough
— Cardinal Del Monte
Noam Almaz
— Boy Caravaggio
Dawn Archibald
— Pipo
Jack Birkett
— The Pope
Una Brandon-Jones
— Weeping Woman
Imogen Claire
— Lady with the Jewels
Sadie Corre
— Princess Collona
Lol Coxhill
— Old Priest
Vernon Dobtcheff
— Art Lover
Terry Downes
— Bodyguard
Jonathan Hyde
— Baglione
Emile Nicolaou
— Young Jerusaleme
Gene October
— Model Peeling Fruit
Cindy Oswin
— Lady Elizabeth
John Rogan
— Vatican Official
Zohra Sehgal
— Jerusaleme's Grandmother
Lucien Taylor
— Boy with Guitar
Simon Fisher-Turner
— Fra Filippo
Derek Jarman
— Papal Aide (uncredited)
Cerith Wyn Evans
— Altar Boy (uncredited)